Acrodynia Due to Mercury Poisoning: A Review of Symptoms and Treatment Options

Mercury poisoning is a serious condition that can have devastating effects on the body. One of the most common forms of mercury toxicity is acrodynia, which is characterized by pink discoloration of the hands and feet, irritability, photophobia (sensitivity to light), and polyneuritis (inflamed nerves). In this article, we will discuss the symptoms and treatment options for acrodynia due to mercury poisoning.

Symptoms of Acrodynia

The symptoms of acrodynia can vary from person to person, but they often include:

* Pink discoloration of the hands and feet

* Irritability

* Photophobia (sensitivity to light)

* Polyneuritis (inflamed nerves)

* Edema and desquamation of the skin on the hands and feet

* Nephrotic syndrome progressing to renal failure in extreme cases

* Extreme photophobia, where the patient burrows their head or covers their eyes to block out light

* Alopecia and nail loss have also been reported.

In addition to these physical symptoms, people with acrodynia may also experience:

* Generalized weakness and painful extremities

* More than 50% complain of sensitivity to light

* Loss of appetite and subsequent weight loss

* Listlessness, drowsiness, irritability, and a tendency to cry

It is important to note that the signs and symptoms of mercury toxicity may not appear until weeks or months after exposure has occurred. The most common form of exposure in young children is ingesting mercury from a broken thermometer.

Treatment Options for Acrodynia

The goal of treatment for acrodynia due to mercury poisoning is to remove the mercury and correct any fluid or electrolyte imbalances. Hemodialysis with and without the addition of L-cysteine as a chelating agent has been used in patients with acute renal failure from mercury toxicity.

Chelating agents such as meso 2,3-dimercaptosuccinic acid are also used to prevent methylmercury uptake by erythrocytes (red blood cells) and hepatocytes (liver cells).

In addition to these medical treatments, it is important for individuals with acrodynia to take steps to reduce their exposure to mercury in their daily lives. This may include avoiding contact with mercury-containing products, such as thermometers or fluorescent light bulbs.

Acrodynia due to mercury poisoning is a serious condition that requires prompt treatment. By understanding the symptoms and treatment options for this condition, individuals can take steps to protect themselves and their loved ones from the devastating effects of mercury toxicity. If you have been exhibiting symptoms of mercury poisoning, it is important to seek medical attention immediately.

References:

* US National Guidelines Clearinghouse on Acrodynia

* C. US National Guidelines Clearinghouse on Acrodynia

* Articles on Acrodynia in N Eng J Med, Lancet, BMJ